![]() Other side effects include headache and antimuscarinic effects, such as urinary retention, dry mouth, blurred vision, and gastrointestinal problems. Adverse effects Īs a "non-sedating" antihistamine, loratadine causes less (but still significant, in some cases) sedation and psychomotor retardation than the older antihistamines, because it penetrates the blood/brain barrier less. In the U.S., it is classified as category B in pregnancy, meaning animal reproduction studies have failed to demonstrate a risk to the fetus, but no adequate and well-controlled studies in pregnant women have been conducted. Loratadine is usually compatible with breastfeeding (classified category L-2 - probably compatible, by the American Academy of Pediatrics). Also available are quick-dissolving tablets. The medication is available in many different forms, including tablets, oral suspension, and syrups. ![]() Dosage forms An example of a loratadine 10-mg tablet (Rx) Loratadine/pseudoephedrine is a fixed dose combination of the drug with pseudoephedrine, a nasal decongestant. Similarly to cetirizine, loratadine attenuates the itching associated with Kimura's disease. For allergic rhinitis, loratadine is indicated for both nasal and eye symptoms including sneezing, runny nose, and itchy or burning eyes. Loratadine is indicated for the symptomatic relief of allergies such as hay fever (allergic rhinitis), urticaria (hives), chronic idiopathic urticaria, and other skin allergies. In 2020, it was the 73rd most commonly prescribed medication in the United States, with more than 9 million prescriptions. In the United States, it is available over the counter. Loratadine is available as a generic medication. It is on the World Health Organization's List of Essential Medicines. Loratadine was patented in 1980 and came to market in 1988. It is in the second-generation antihistamine family of medication. It is not recommended in children less than two years old. Use during pregnancy appears to be safe but has not been well studied. Serious side effects are rare and include allergic reactions, seizures, and liver problems. Ĭommon side effects include sleepiness, dry mouth, and headache. It is also available in drug combinations such as loratadine/pseudoephedrine, in which it is combined with pseudoephedrine, a nasal decongestant. This includes allergic rhinitis (hay fever) and hives. Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies.
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